Dirt and Disease is a social, cultural, and medical history of the polio epidemic in the United States. Naomi Rogers focuses on the early years from 1900 to 1920, and continues the story to the present. She explores how scientists, physicians, patients, and their families explained the appearance and spread of polio and how they tried to cope with it. Rogers frames this study of polio within a set of larger questions about health and disease in twentieth-century American culture.